No, Trillian is currently only available as a Windows software. Trillian Astra will introduce a web-based version that can be used in a browser (and therefore also on Linux or Macintosh computers). The core code of Trillian Astra compiles under Linux and Mac OS X, but that is just a first step and does not mean that a usable Trillian version for these systems can be easily created.
An alternative for Mac OS X is Adium X.
An alternative for Linux is Kopete or Pidgin (formerly known as Gaim).